Neuropathology, Localized Proteomics, and Imaging of the Choroid Plexus across the Alzheimer's Disease Continuum
We performed an initial characterization of the ChP by MRI and neuropathology, and identified proteomic differences in AD. Our results provide valuable insights into molecular mechanisms, novel diagnostic biomarkers, and potential therapeutic strategies.
Authors
- Orrin Devinsky (ORCID: https://orcid.org/0000-0003-0044-4632)
- Youssef Zaim Wadghiri (ORCID: https://orcid.org/0000-0001-7175-9397)
- Dominique Leitner (ORCID: https://orcid.org/0000-0002-1371-9861)
- Arline Faustin (ORCID: https://orcid.org/0000-0002-1147-9665)
- Huize Pang (ORCID: https://orcid.org/0009-0006-3930-8178)
- Mary T. Bruno (ORCID: https://orcid.org/0000-0003-1625-0293)
- Evgeny Kanshin (ORCID: https://orcid.org/0000-0001-7142-4554)
- Chenyang Li (ORCID: https://orcid.org/0000-0001-8109-9388)
- Beatrix Ueberheide
- Jiangyang Zhang
- Yulin Ge
- Thomas Wisniewski
Institutions
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105614
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00