Acute Renal Infarction as an Initial Manifestation of Factor V Leiden Mutation: A Case Report

Factor V Leiden is one of the most prevalent forms of inherited thrombophilia. While its usual presentation is a deep vein thrombosis and pulmonary embolism, it can manifest less commonly as a renal infarction. Here, we describe a case of a previously healthy woman who was found to have a renal infarction triggered by a hypercoagulable state associated with the Factor V Leiden mutation. This case highlights the importance of considering thrombophilia as a differential diagnosis in cases of insidious acute renal infarction, especially in patients with no identified risk factors.