Core Activation Program and Selective Regional Responsiveness of Microglia in Aging and Parabiosis
This work highlights the regional variation in microglial subpopulation transcriptomic dynamics during aging and under rejuvenation conditions, providing insights into differential brain regional vulnerability and offering potential avenues for microglia-targeted modulation of brain aging.
Authors
- Huma Naz (ORCID: https://orcid.org/0000-0003-4393-5378)
- Róbert Pálovics (ORCID: https://orcid.org/0000-0003-0202-7760)
- Shinnosuke Yamada (ORCID: https://orcid.org/0009-0000-0209-4942)
- Guoyan Zhao
- Tony Wyss‐Coray
- Qingyun Li
- Nannan Lu
Institutions
- Neurosciences Institute (US)
- Washington University in St. Louis (US)
- Stanford University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106438
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00