Genetic risk and plasma biomarkers of dementia with Lewy bodies in a Chinese population
This research is the first genetic investigation of DLB in East Asia. We found that APOE ε4 and rare variant of USP13 gene significantly increased the risk of DLB, highlighting the discriminative ability for DLB using PRS and plasma biomarkers assay.
Authors
- Ling Weng
- Bing Tang (ORCID: https://orcid.org/0000-0001-5859-8250)
- Xiaoli Hao
- Jian‐Bin Li (ORCID: https://orcid.org/0000-0002-8995-3304)
- J. Guo
- Xuewen Xiao
- Bin Jiao
- Lu Shen
- Xinxiang Yan
- Junling Wang
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_100125
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00