Identification of coagulation-related hub genes in ischemic stroke based on bioinformatics integration analysis and investigation of their immune regulatory mechanisms
The two hub genes, C5AR1 and MYH9, may contribute to the development of IS by promoting thrombosis. These findings offer new insights into the molecular mechanisms of IS and suggest potential biomarkers and therapeutic targets for IS management.
Authors
- M J Chen
- Hepeng Li (ORCID: https://orcid.org/0000-0001-8779-9553)
- Lan Yuan (ORCID: https://orcid.org/0000-0003-1595-8951)
- Junli Liang
Institutions
- Guangxi Medical University (CN)
- Guangxi University of Chinese Medicine (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- The Second Nanning People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s40001-025-03477-4
- Citations
- 1
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80