Mass Spectral Studies of <i>N</i> , <i>N</i> ‐Dialkylacetimidamides Using ESI‐HRMS and MS/MS
A series of amidines (1-10) including three isomeric sets (3-5, 6-7, and 8-10) were synthesized and characterized by ESI-HRMS and MS/MS, and nuclear magnetic resonance (<sup>1</sup>H NMR) spectroscopic methods. All the isomeric compounds were differentiated based on their tandem mass spectral data. This method was successfully demonstrated to identify spiked amidines in the 56th and 57th OPCW official proficiency test samples.
Authors
- Swarajya Lakshmi Vattem Venkata
- Ramunaidu Addipilli
- Srinivas Kantevari (ORCID: https://orcid.org/0000-0003-4270-9651)
- Pranay Renukuntla (ORCID: https://orcid.org/0009-0009-0663-1130)
- Manasa Masna
- Sandhya Bobbali (ORCID: https://orcid.org/0009-0000-0725-5776)
- S. Babu Dadinaboyina
- Nikita Singh M
- Jagadeshwar Reddy Thota
Institutions
- Indian Institute of Chemical Technology (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1002/rcm.70015
- Citations
- 2
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.51
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Indian Council of Medical Research