Analyzing choroid plexus volume in association with mild behavioral impairment and progression to dementia
MBI+ participants had higher CP volumes, and both MBI+ status and CP volumes independently predicted incident dementia. While MBI did not moderate the CP-dementia association, it might serve as a mediator, warranting further research. These findings support MBI as a clinical tool for identifying dementia risk, and highlight CP volume as a potential neuroimaging biomarker.
Authors
- Dylan X. Guan (ORCID: https://orcid.org/0000-0002-7065-1963)
- Maryam Ghahremani (ORCID: https://orcid.org/0000-0001-8063-713X)
- Zahinoor Ismail
- Sabika Azhar
Institutions
- University of Calgary (CA)
- Hotchkiss Brain Institute (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097751
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00