The Contribution of Long Noncoding RNAs to Worse Cognitive Function in Alzheimer's Disease

Multi-omics analyses identified lncRNAs linked to worse cognitive function in AD. We hypothesize that WCFAL1 regulates microglial activity via FOXN3 or facilitates FOXN3-SIN3A interaction. Future studies will validate this through WCFAL1 overexpression or knockdown experiments.

Authors

Abdallah M. Eteleeb (ORCID: https://orcid.org/0000-0001-9045-250X)

Institutions

Washington University in St. Louis (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70855_103150
Primary Topic: Cancer-related molecular mechanisms research
Type: article
Field-Weighted Citation Impact: 0.00

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article

The Contribution of Long Noncoding RNAs to Worse Cognitive Function in Alzheimer's Disease

Abdallah M. Eteleeb

Dec 1, 2025

Alzheimer s & Dementia

Cancer-related molecular mechanisms research

article

The Contribution of Long Noncoding RNAs to Worse Cognitive Function in Alzheimer's Disease

Abdallah M. Eteleeb

December 1, 2025article en

Abstract

Alzheimer s & DementiaVol. 21(S1)

Washington University in St. Louis (US)

Openalex Percentile: Top 34%

Cancer-related molecular mechanisms research

DOI Open Access PDF OpenAlex

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The Contribution of Long Noncoding RNAs to Worse Cognitive Function in Alzheimer's Disease — Abdallah M. Eteleeb · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS