Meta‐Analysis of Mean Differences and Diagnostic Accuracy of Ptau‐217 in Amyloid‐Positive and Amyloid‐Negative Cognitively Unimpaired Older Adults

Plasma assays for ptau-217 can accurately identify individuals in the preclinical phase of AD and the large effect size for mean differences between amyloid-positive and amyloid-negative individuals provides further support for the use of ptau-217 as a diagnostic tool in identifying preclinical AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_096180
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
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article

Meta‐Analysis of Mean Differences and Diagnostic Accuracy of Ptau‐217 in Amyloid‐Positive and Amyloid‐Negative Cognitively Unimpaired Older Adults

Fawaz Stipho, Nicholas Ashton, Savar Sharma, Michael H. Malek‐Ahmadi
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Meta‐Analysis of Mean Differences and Diagnostic Accuracy of Ptau‐217 in Amyloid‐Positive and Amyloid‐Negative Cognitively Unimpaired Older Adults

Fawaz Stipho, Nicholas Ashton, Savar Sharma, Michael H. Malek‐Ahmadi
article en

Abstract

Plasma assays for ptau-217 can accurately identify individuals in the preclinical phase of AD and the large effect size for mean differences between amyloid-positive and amyloid-negative individuals provides further support for the use of ptau-217 as a diagnostic tool in identifying preclinical AD.

Alzheimer s & DementiaVol. 21(S2)
Alzheimer's Association (US), University of Arizona (US), University of Phoenix (US), Banner Sun Health Research Institute (US), Banner Alzheimer’s Institute, Arizona Alzheimer’s Consortium, Glendale Community College (US), Phoenix College (US)
Quality Education
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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Meta‐Analysis of Mean Differences and Diagnostic Accuracy of Ptau‐217 in Amyloid‐Positive and Amyloid‐Negative Cognitively Unimpaired Older Adults — Fawaz Stipho, Nicholas Ashton, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS