Determining eligibility for anti‐amyloid treatments using blood biomarkers

In 21 patients who underwent a second test with CSF or PET, all 15 patients who were positive by PrecivityAD2 were also positive by CSF or PET. Although this study is very small, these data support providing anti-amyloid treatments based on high accuracy blood biomarker tests to patients with a high clinical likelihood of amyloid pathology.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_097511
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Determining eligibility for anti‐amyloid treatments using blood biomarkers

Madeline Paczynski, Melissa Aldinger, Barbara J. Snider, Zachary J Posey et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
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Determining eligibility for anti‐amyloid treatments using blood biomarkers

Madeline Paczynski, Melissa Aldinger, Barbara J. Snider, Zachary J Posey, John C. Morris, Tammie L.S. Benzinger, Anna Hofmann, Suzanne E. Schindler
article en

Abstract

In 21 patients who underwent a second test with CSF or PET, all 15 patients who were positive by PrecivityAD2 were also positive by CSF or PET. Although this study is very small, these data support providing anti-amyloid treatments based on high accuracy blood biomarker tests to patients with a high clinical likelihood of amyloid pathology.

Alzheimer s & DementiaVol. 21(S2)
Washington University in St. Louis (US)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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