Photoinduced iridium-cobaloxime mediated alkene C(sp <sup>2</sup> )–CF <sub>2</sub> H cross-coupling: difluoromethylation of ketene dithioacetals

Photoinduced difluoromethylation of ketene dithioacetals under mild conditions has been developed, realizing the challenging alkene C(sp 2 )–CF 2 H cross-coupling reaction and mechanistically proving the crucial role of cobaloxime under mild conditions.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-12-24
DOI
https://doi.org/10.1039/d5qo01628b
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00
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article

Photoinduced iridium-cobaloxime mediated alkene C(sp 2 )–CF 2 H cross-coupling: difluoromethylation of ketene dithioacetals

Long Sun, Junsheng Zhi, Qun Liu, Yifei Li et al.
Organic Chemistry Frontiers
Fluorine in Organic Chemistry
article

Photoinduced iridium-cobaloxime mediated alkene C(sp 2 )–CF 2 H cross-coupling: difluoromethylation of ketene dithioacetals

Long Sun, Junsheng Zhi, Qun Liu, Yifei Li, Ling Pan, Baoping Ren
article en

Abstract

Photoinduced difluoromethylation of ketene dithioacetals under mild conditions has been developed, realizing the challenging alkene C(sp 2 )–CF 2 H cross-coupling reaction and mechanistically proving the crucial role of cobaloxime under mild conditions.

Organic Chemistry FrontiersVol. 13(4)
Northeast Normal University (CN)
Openalex Percentile: Top 37%
Fluorine in Organic Chemistry
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