The NGF Metabolic Pathway is altered in a Rat Model of Human‐like Tauopathy

Our studies in McGill-R955-hTau rats would indicate that the advanced tauopathy provokes an additional dysregulation of the brain's NGF metabolic pathway leading to an exacerbated forebrain cholinergic atrophy.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_103151
Primary Topic
Nerve injury and regeneration
Type
article
Field-Weighted Citation Impact
0.00
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article

The NGF Metabolic Pathway is altered in a Rat Model of Human‐like Tauopathy

Liu Ai, Joshua T. Emmerson, Sonia Do Carmo, Quentin Bonomo et al.
Alzheimer s & Dementia
Nerve injury and regeneration
article

The NGF Metabolic Pathway is altered in a Rat Model of Human‐like Tauopathy

Liu Ai, Joshua T. Emmerson, Sonia Do Carmo, Quentin Bonomo, Chloé Levasseur, A. Claudio Cuello, Cynthia Sun
article en

Abstract

Our studies in McGill-R955-hTau rats would indicate that the advanced tauopathy provokes an additional dysregulation of the brain's NGF metabolic pathway leading to an exacerbated forebrain cholinergic atrophy.

Alzheimer s & DementiaVol. 21(S1)
University of Oxford (GB), McGill University (CA)
Reduced inequalities
Openalex Percentile: Top 38%
Nerve injury and regeneration
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