Alzheimer's Disease as Type 3 Diabetes: The Impact of Insulin Resistance and the Therapeutic Potential of Semaglutide in Cognitive Decline

While initial evidence is encouraging, long-term safety, optimal dosage, and impact on AD progression remain unclear. If proven effective, semaglutide could serve as a dual-purpose drug, addressing both metabolic dysfunction and neurodegeneration.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_103762
Primary Topic
Diabetes Treatment and Management
Type
article
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0.00
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article

Alzheimer's Disease as Type 3 Diabetes: The Impact of Insulin Resistance and the Therapeutic Potential of Semaglutide in Cognitive Decline

Deepesh Khanna, A. Singh, Monica Kumar, Kirpal Bains et al.
Alzheimer s & Dementia
Diabetes Treatment and Management
article

Alzheimer's Disease as Type 3 Diabetes: The Impact of Insulin Resistance and the Therapeutic Potential of Semaglutide in Cognitive Decline

Deepesh Khanna, A. Singh, Monica Kumar, Kirpal Bains, Isha Verma
article en

Abstract

While initial evidence is encouraging, long-term safety, optimal dosage, and impact on AD progression remain unclear. If proven effective, semaglutide could serve as a dual-purpose drug, addressing both metabolic dysfunction and neurodegeneration.

Alzheimer s & DementiaVol. 21(S1)
Nova Southeastern University (US)
Reduced inequalities
Openalex Percentile: Top 30%
Diabetes Treatment and Management
DOIOpen Access PDFOpenAlex
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Alzheimer's Disease as Type 3 Diabetes: The Impact of Insulin Resistance and the Therapeutic Potential of Semaglutide in Cognitive Decline — Deepesh Khanna, A. Singh, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS