Polygenic Risk Scores for Amyloidosis as Predictors of Early changes in Alzheimer's Disease Endophenotypes
Amyloid PRSs show promise as predictive tools for early AD pathology in asymptomatic individuals among Europeans and Caribbean Hispanics.
Authors
- Martin Medrano (ORCID: https://orcid.org/0000-0003-3673-9088)
- Belisa Soriano
- Patricia Recio
- Diones Rivera Mejía (ORCID: https://orcid.org/0000-0001-5935-8005)
- Yuexuan Xu (ORCID: https://orcid.org/0000-0002-2732-7199)
- Tamil Iniyan Gunasekaran (ORCID: https://orcid.org/0000-0002-8639-5060)
- Rachael E. Wilson (ORCID: https://orcid.org/0000-0003-4197-7777)
- Corinne D. Engelman (ORCID: https://orcid.org/0000-0003-4750-5607)
- Danurys Sanchez (ORCID: https://orcid.org/0000-0001-8273-0952)
- Zoraida Dominguez Coronado
- Angel Piriz
- Dolly Reyes‐Dumeyer (ORCID: https://orcid.org/0000-0003-3572-8248)
- Rafael Lantigua (ORCID: https://orcid.org/0000-0003-4854-7331)
- Yahaira Franco
- Ramiro Eduardo Rea Reyes (ORCID: https://orcid.org/0000-0001-9749-282X)
- Min N Qiao
- Sanjay Asthana (ORCID: https://orcid.org/0000-0002-3998-4479)
- R Mayeux
- Adam Brickman
- Sterling C Johnson
- Badri N. Vardarajan
- Yian Gu
- Jennifer J. Manly
Institutions
- NewYork–Presbyterian Hospital (US)
- University of Wisconsin–Madison (US)
- Pontificia Universidad Católica Madre y Maestra (DO)
- Columbia University Irving Medical Center (US)
- New York Hospital Queens (US)
- Instituto Tecnológico de Santo Domingo (DO)
- Universidad Nacional Pedro Henríquez Ureña (DO)
- University of Wisconsin Health (US)
- Universidad Dr. José Gregorio Hernández (VE)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101027
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00