Multimodal artificial intelligence in retinal vascular and neovascular macular diseases: a systematic review of diagnostic and prognostic applications

Multimodal AI demonstrates superior diagnostic and prognostic performance compared to unimodal models and, in some cases, outperforms expert clinicians in managing retinal vascular diseases. Integrating complementary data sources, such as OCT, fundus imaging, and clinical information, enhances model accuracy and generalizability.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-12-24
DOI
https://doi.org/10.1186/s12886-025-04561-3
Primary Topic
Retinal Imaging and Analysis
Type
article
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article

Multimodal artificial intelligence in retinal vascular and neovascular macular diseases: a systematic review of diagnostic and prognostic applications

Mohamed Baklola, Ghadah Almutairi, Amani A Al Ghramah, Razan Alshehri et al.
BMC Ophthalmology
Retinal Imaging and Analysis
article

Multimodal artificial intelligence in retinal vascular and neovascular macular diseases: a systematic review of diagnostic and prognostic applications

Mohamed Baklola, Ghadah Almutairi, Amani A Al Ghramah, Razan Alshehri, Naji Al-Bawah, Khaled AbdelKhalique abdelshafi Ghaith, Amal Turki Aljuaid, Abdulmajeed Al Khathami, Raghad Sayyaf Alshahrani, Orjuwan Turki Aljuaid, Reema Hasan AlGarni, Meshari Ahmed Alalyani, Rawan Saud Aldreweash, Safiyah Abdullah Albishi, Rehab Alsaeed
article en

Abstract

Multimodal AI demonstrates superior diagnostic and prognostic performance compared to unimodal models and, in some cases, outperforms expert clinicians in managing retinal vascular diseases. Integrating complementary data sources, such as OCT, fundus imaging, and clinical information, enhances model accuracy and generalizability.

BMC OphthalmologyVol. 26(1)
Mansoura University (EG), Sana'a University (YE), King Saud bin Abdulaziz University for Health Sciences (SA), Majmaah University (SA), King Saud University (SA), University of Bisha (SA), King Fahad Hospital Jeddah (SA), National Guard Health Affairs (SA), Al Baha University (SA), Imam Abdulrahman Bin Faisal University (SA)
Openalex Percentile: Top 31%
Retinal Imaging and Analysis
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Multimodal artificial intelligence in retinal vascular and neovascular macular diseases: a systematic review of diagnostic and prognostic applications — Mohamed Baklola, Ghadah Almutairi, et al. · BMC Ophthalmology (2025) | TGRS Research Map | TGRS