APOE epistasis as population specific risk factors for Alzheimer's Disease outcomes
This study begins elucidating disease comorbidity and gene-gene interactions as a potential considerations for predicting AD risk, specifically a co-occurance of RAAS gene SNPs with APOE, and supports future mechanistic studies on cellular phenotypes associated with epistatic effects.
Authors
- Harlan P. Jones (ORCID: https://orcid.org/0000-0003-3248-0355)
- Robert Barber
- Nicole Phillips
- Amanda Elizabeth Tucker
Institutions
- University of North Texas (US)
- University of North Texas Health Science Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_103802
- Primary Topic
- Renin-Angiotensin System Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00