Effect of trophic factor on single vascular insult induced amyloid accumulation with AD mice
Vascular insult has varied response in slow progressing APPswe mice and fast progressing J20 mice in terms of susceptibility. This was reflected across age with increasing changes in BBB integrity. Pretreatment of trophic factor PTN was able to prevent BBB dysfunction caused by ET-1 injection.
Authors
- Rehab Hussain
- Latha Diwakar (ORCID: https://orcid.org/0000-0003-0515-2428)
- Mayank Pushpam
Institutions
- Manipal Academy of Higher Education (IN)
- Indian Institute of Science Bangalore (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106567
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00