Antroquinonol reduces IL-1β production in macrophages through enhancing the DNA methylation of Tlr4
Our study elucidates a multi-pathway for the anti-inflammatory effects of Antro, significantly enriching the theoretical framework of natural product-mediated immunomodulation (particularly plant/fungal extracts). These findings provide critical scientific support for developing <i>A. camphorata</i>-derived fermentation products as novel feed additives to enhance immune function in swine production.
Authors
- Zhaodi Fu
- Wenjin Peng
- Kaijun Wang
- Chunxue Liu
- Peng Bin
- Zixu Wang
- Jiahao Mo
- Ifen Hung
Institutions
- South China Agricultural University (CN)
- Changsha Medical University (CN)
- Hunan Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-12-24
- DOI
- https://doi.org/10.3389/fnut.2025.1742566
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China