Quantitation of Alzheimer's disease biomarkers in plasma using SMC <sup>®</sup> high sensitivity immunoassays

This study demonstrates the value of using multiplex high sensitivity technology to evaluate multiple biomarkers in the same sample. The SMC<sup>®</sup> Aβ42/Aβ40 high sensitivity immunoassay kit serves as a powerful non-invasive biomarker tool for monitoring the progression of neurodegenerative diseases such as Alzheimer's disease while saving time and sample. Further studies into other combinations of AD biomarkers will determine if their ratios would also serve as valuable measures of AD related neurodegeneration.

Authors

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101217
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Quantitation of Alzheimer's disease biomarkers in plasma using SMC ® high sensitivity immunoassays

Deborah A. Droll, Elizabeth Adkisson, Joseph Hwang, Rick Wiese et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Quantitation of Alzheimer's disease biomarkers in plasma using SMC ® high sensitivity immunoassays

Deborah A. Droll, Elizabeth Adkisson, Joseph Hwang, Rick Wiese, Raad Gitan
article en

Abstract

This study demonstrates the value of using multiplex high sensitivity technology to evaluate multiple biomarkers in the same sample. The SMC<sup>®</sup> Aβ42/Aβ40 high sensitivity immunoassay kit serves as a powerful non-invasive biomarker tool for monitoring the progression of neurodegenerative diseases such as Alzheimer's disease while saving time and sample. Further studies into other combinations of AD biomarkers will determine if their ratios would also serve as valuable measures of AD related neurodegeneration.

Alzheimer s & DementiaVol. 21(S2)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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