Sugars to signals: emerging roles of PAK1 in re-wiring glucose metabolism in cancers
An ideal biodegradable drug delivery system and an appropriately representative pre-clinical model exploiting the Warburg effect could enhance targeted delivery and therapeutic efficacy, and could help advance tumor targeted therapies in aggressive cancers like TNBC and pancreatic cancer.
Authors
- Prarthana Gopinath (ORCID: https://orcid.org/0000-0003-1763-8556)
- Ganesh Venkatraman (ORCID: https://orcid.org/0000-0003-3073-7997)
- Srikanth Swamy Swaroop B
- Suresh K. Rayala (ORCID: https://orcid.org/0000-0003-4394-4450)
Institutions
- Sri Ramachandra Institute of Higher Education and Research (IN)
- Indian Institute of Technology Madras (IN)
- Vellore Institute of Technology University (IN)
Publication Details
- Journal
- Expert Opinion on Therapeutic Targets
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1080/14728222.2025.2608032
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00