Novel insights on Nerve growth factor mediated regulation of immune response
Our results show that all the immune cells which we examined express NGF receptor TrkA, thus possessing the ability to respond to NGF. Our findings suggest, that NGF-TrkA signaling can modulate the immune response in T cells by reducing inflammatory cytokine production.
Authors
- Simone Tambaro (ORCID: https://orcid.org/0000-0001-7000-7556)
- Ruchi Gera (ORCID: https://orcid.org/0000-0002-7043-4096)
- Maria Eriksdotter
- Sumonto Mitra
- Per Nilsson
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102734
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00