Relating Physical Activity to Cognitive Function, Brain Morphology, and AD‐related Blood Biomarkers: Preliminary Findings from the IGNITE study
Preliminary findings emphasize the relationship of fitness and PA to cognition, multiple aspects of brain morphology, and AD-related blood biomarkers in cognitively unimpaired older adults. This research also identifies multiple moderators of these relationships, which may help inform individualized exercise prescriptions to optimize cognitive and brain health in older adulthood.
Authors
- Lauren B. Raine (ORCID: https://orcid.org/0000-0002-6679-9551)
- Kirk I. Erickson (ORCID: https://orcid.org/0000-0001-8736-981X)
- George Grove (ORCID: https://orcid.org/0000-0002-5043-139X)
- Audrey M. Collins
- Haiqing Huang (ORCID: https://orcid.org/0000-0003-1240-6641)
- Lauren E. Oberlin (ORCID: https://orcid.org/0000-0001-9553-8070)
- Jill K. Morris (ORCID: https://orcid.org/0000-0001-5911-4190)
- John M. Jakicic (ORCID: https://orcid.org/0000-0001-6800-9368)
- Kelsey R. Sewell (ORCID: https://orcid.org/0000-0002-3859-5017)
- Jeffrey Murray Burns (ORCID: https://orcid.org/0000-0001-7609-8954)
- Chaeryon Kang (ORCID: https://orcid.org/0000-0001-9442-8515)
- Cristina Molina‐Hidalgo (ORCID: https://orcid.org/0000-0002-5483-5666)
- Eric Dennis Vidoni
- Lu Wan
- Edward McAuley
- Charles Hillman
- Anna Marsland
- Patricio Solis‐Urra
- Emma Tinney
- Thomas K Karikari
- Arthur F. Kramer
- Hayley Ripperger
Institutions
- Northeastern University (US)
- University of Kansas (US)
- University of Pittsburgh (US)
- Cornell University (US)
- AdventHealth Orlando (US)
- University of Illinois System (US)
- Alzheimer’s Disease Neuroimaging Initiative (US)
- University of Kansas Medical Center (US)
- Translational Research Institute for Metabolism and Diabetes (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102756
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00