Non‐amnestic AD syndrome would exhibit WM differences from amnestic and other non‐amnestic syndromes
We replicated findings of lower WM connectivity in non-amnestic than amnestic AD and showed WM integrity was associated with tau burden and atrophy in tract endpoints. Results were consistent across syndromes with differing cognitive symptoms and disease distributions.
Authors
- Ilya M. Nasrallah (ORCID: https://orcid.org/0000-0003-2346-7562)
- Philip A. Cook (ORCID: https://orcid.org/0000-0002-1985-8475)
- L. Shaw
- Lauren Massimo
- Jeffrey S. Phillips (ORCID: https://orcid.org/0000-0003-0079-9441)
- Christopher A. Olm (ORCID: https://orcid.org/0000-0002-4858-2359)
- Hamsanandini Radhakrishnan (ORCID: https://orcid.org/0000-0002-4448-986X)
- Allison Snyder (ORCID: https://orcid.org/0000-0002-1857-928X)
- Briar Nowling
- Katheryn A. Q. Cousins
- David J. Irwin
- Corey T. McMillan
Institutions
- Penn Center for AIDS Research (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097701
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00