Signatures of resolution reprogramming in the 5xFAD mouse model
We have demonstrated that RvE1 modulates inflammation in a mouse model and in a microglial cell line. Resolution pathways may represent drugable targets to reduce neuroinflammation associated with neuropathology, but a more thorough understanding of how RvE1 achieves therapeutic benefits is needed.
Authors
- Galina Kondrikova
- Dariusz Pytel (ORCID: https://orcid.org/0000-0002-3849-7716)
- Eric D. Hamlett (ORCID: https://orcid.org/0000-0002-2900-7949)
Institutions
- Medical University of South Carolina (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105663
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00