Heteromeric amyloid filaments of TDP‐43 and annexin A11 in neurodegenerative diseases

This work establishes a central role for ANXA11 in neurodegenerative diseases. The unprecedented formation of heteromeric amyloid filaments in the human brain revises our understanding of amyloid assembly and may be of significance for the pathogenesis of neurodegenerative diseases.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_104408
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
0.00
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article

Heteromeric amyloid filaments of TDP‐43 and annexin A11 in neurodegenerative diseases

Ben Falcon
Alzheimer s & Dementia
S100 Proteins and Annexins
article

Heteromeric amyloid filaments of TDP‐43 and annexin A11 in neurodegenerative diseases

Ben Falcon
article en

Abstract

This work establishes a central role for ANXA11 in neurodegenerative diseases. The unprecedented formation of heteromeric amyloid filaments in the human brain revises our understanding of amyloid assembly and may be of significance for the pathogenesis of neurodegenerative diseases.

Alzheimer s & DementiaVol. 21(S1)
MRC Laboratory of Molecular Biology (GB)
Openalex Percentile: Top 36%
S100 Proteins and Annexins
DOIOpen Access PDFOpenAlex
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