Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study

The MPGx-INDALL (Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children) study will generate actionable insights for individualized ALL therapy in India via systematically evaluating germline and somatic markers in a large ethnically distinct cohort.

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Publication Details

Journal
JMIR Research Protocols
Published
2025-12-24
DOI
https://doi.org/10.2196/79865
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
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article

Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study

Swaminathan Keerthivasagam, Swetambri Sharma, Smita Kayal, Frederic Belaydier et al.
JMIR Research Protocols
Acute Lymphoblastic Leukemia research
article

Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study

Swaminathan Keerthivasagam, Swetambri Sharma, Smita Kayal, Frederic Belaydier, Kamali Murugadoss, Shuvadeep Ganguly
article en

Abstract

The MPGx-INDALL (Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children) study will generate actionable insights for individualized ALL therapy in India via systematically evaluating germline and somatic markers in a large ethnically distinct cohort.

JMIR Research ProtocolsVol. 15
University of Geneva (CH), University Hospital of Geneva (CH), Jawaharlal Institute of Post Graduate Medical Education and Research (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 27%
Acute Lymphoblastic Leukemia research
DOIOpen Access PDFOpenAlex
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Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study — Swaminathan Keerthivasagam, Swetambri Sharma, et al. · JMIR Research Protocols (2025) | TGRS Research Map | TGRS