Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications

The availability of sequence polymorphism data and the increased number of STR loci could enhance the efficacy of the detection systems for kinship identifications to a certain extent. These results highlight the potential of combining length and sequence polymorphisms of STRs in forensic practice, offering a valuable tool for addressing the challenge of complex kinship identification. Future research should validate these thresholds in casework samples and expand the number of STR loci to enhance the detection efficacy for distant relationships.

Authors

Institutions

Publication Details

Journal
Human Genomics
Published
2025-12-24
DOI
https://doi.org/10.1186/s40246-025-00858-y
Citations
1
Primary Topic
Forensic and Genetic Research
Type
article
Field-Weighted Citation Impact
1.82

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications

Hui Xu, Qinglin Liu, Hongbing Yao, Xi Yuan et al.
1 citations
Human Genomics
Forensic and Genetic Research
1.82
article

Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications

Hui Xu, Qinglin Liu, Hongbing Yao, Xi Yuan, Xiying Wu, Bofeng Zhu, Yifeng Lin, Lisiteng Luo, Qinglin Liang, Qiong Lan
article en
1 citations

Abstract

The availability of sequence polymorphism data and the increased number of STR loci could enhance the efficacy of the detection systems for kinship identifications to a certain extent. These results highlight the potential of combining length and sequence polymorphisms of STRs in forensic practice, offering a valuable tool for addressing the challenge of complex kinship identification. Future research should validate these thresholds in casework samples and expand the number of STR loci to enhance the detection efficacy for distant relationships.

Human GenomicsVol. 19(1)
Shanxi Medical University (CN), Zhujiang Hospital (CN), Gansu Institute of Political Science and Law (CN), Southern Medical University (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China
Reduced inequalities
Openalex Percentile: Top 10%
Forensic and Genetic Research
1.82
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.