Forensic utilization of NGS-STRs and evaluation of system efficacy for different kinship identifications
The availability of sequence polymorphism data and the increased number of STR loci could enhance the efficacy of the detection systems for kinship identifications to a certain extent. These results highlight the potential of combining length and sequence polymorphisms of STRs in forensic practice, offering a valuable tool for addressing the challenge of complex kinship identification. Future research should validate these thresholds in casework samples and expand the number of STR loci to enhance the detection efficacy for distant relationships.
Authors
- Hui Xu (ORCID: https://orcid.org/0000-0001-5517-3556)
- Qinglin Liu
- Hongbing Yao
- Xi Yuan (ORCID: https://orcid.org/0000-0002-1865-530X)
- Xiying Wu (ORCID: https://orcid.org/0000-0002-9703-2863)
- Bofeng Zhu
- Yifeng Lin
- Lisiteng Luo
- Qinglin Liang
- Qiong Lan
Institutions
- Shanxi Medical University (CN)
- Zhujiang Hospital (CN)
- Gansu Institute of Political Science and Law (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1186/s40246-025-00858-y
- Citations
- 1
- Primary Topic
- Forensic and Genetic Research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China