Identification of potential characteristic genes in sepsis utilizing RNA sequencing and gene silence

Notably, S100A11 was found to be highly expressed in patients with sepsis. This gene plays a crucial role in promoting inflammation during the septic inflammatory response and may be involved in macrophage differentiation, immunomodulation, and the inflammatory processes associated with sepsis.

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Publication Details

Journal
BMC Immunology
Published
2025-12-24
DOI
https://doi.org/10.1186/s12865-025-00778-5
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of potential characteristic genes in sepsis utilizing RNA sequencing and gene silence

F. Wang, Jincheng Li, Jie Yang, Wu Wang et al.
BMC Immunology
S100 Proteins and Annexins
article

Identification of potential characteristic genes in sepsis utilizing RNA sequencing and gene silence

F. Wang, Jincheng Li, Jie Yang, Wu Wang, Wei Wu, Zhou Huang, Hongying Cao, Chunyang Dong, Nianying Qin, Dongling Huang, Yiling Zhai
article en

Abstract

Notably, S100A11 was found to be highly expressed in patients with sepsis. This gene plays a crucial role in promoting inflammation during the septic inflammatory response and may be involved in macrophage differentiation, immunomodulation, and the inflammatory processes associated with sepsis.

BMC ImmunologyVol. 26(1)
Guangxi Medical University (CN), Affiliated Hospital of Southwest Medical University (CN), Longgang Central Hospital (CN), First People's Hospital of Foshan (CN), First Affiliated Hospital of GuangXi Medical University (CN), 181st Hospital of Chinese People's Liberation Army (CN), Affiliated Hospital of Guilin Medical College (CN)
Good health and well-being
Openalex Percentile: Top 36%
S100 Proteins and Annexins
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Identification of potential characteristic genes in sepsis utilizing RNA sequencing and gene silence — F. Wang, Jincheng Li, et al. · BMC Immunology (2025) | TGRS Research Map | TGRS