Extramedullary plasmacytoma of the tibial nerve: illustrative case

This case highlights a rare occurrence of peripheral nerve invasion by an EMP with the first documented involvement of the tibial nerve. This report suggests that EMPs should be considered in the differential diagnosis of PNSTs, particularly in MM patients. The present case underscores the need for intraoperative biopsies in PNST resection, as imaging features alone may not be fully diagnostic. https://thejns.org/doi/10.3171/CASE25104.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-12-22
DOI
https://doi.org/10.3171/case25104
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Extramedullary plasmacytoma of the tibial nerve: illustrative case

Parsa Nilchian, Gary Kocharian, Kai-Ming Fu, Andrew B. Yang et al.
Journal of Neurosurgery Case Lessons
Multiple Myeloma Research and Treatments
article

Extramedullary plasmacytoma of the tibial nerve: illustrative case

Parsa Nilchian, Gary Kocharian, Kai-Ming Fu, Andrew B. Yang, Max Reed
article en

Abstract

This case highlights a rare occurrence of peripheral nerve invasion by an EMP with the first documented involvement of the tibial nerve. This report suggests that EMPs should be considered in the differential diagnosis of PNSTs, particularly in MM patients. The present case underscores the need for intraoperative biopsies in PNST resection, as imaging features alone may not be fully diagnostic. https://thejns.org/doi/10.3171/CASE25104.

Journal of Neurosurgery Case LessonsVol. 10(25)
NewYork–Presbyterian Hospital (US), Cornell University (US), New York Hospital Queens (US), Presbyterian Hospital (US), Neurological Surgery (US), Weill Cornell Medicine (US)
U.S. Department of Health and Human Services, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 25%
Multiple Myeloma Research and Treatments
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