Maternal and early life exposure induced AD‐ like pathophysiology and its mitigation by allicin

The results indicate the transgenerational effect of lead in inducing AD-like pathophysiology even at 6-month-old F1 progeny. Allicin treated groups showed a significant decrease in the effects indicating its chelating and neuroprotective effect. This study emphasises the transgenerational neurotoxic effect of lead, leading to early onset of major neurodegenerative disorders and its therapeutic interventions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_102556
Primary Topic
Garlic and Onion Studies
Type
article
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article

Maternal and early life exposure induced AD‐ like pathophysiology and its mitigation by allicin

Aluru Parithathvi
Alzheimer s & Dementia
Garlic and Onion Studies
article

Maternal and early life exposure induced AD‐ like pathophysiology and its mitigation by allicin

Aluru Parithathvi
article en

Abstract

The results indicate the transgenerational effect of lead in inducing AD-like pathophysiology even at 6-month-old F1 progeny. Allicin treated groups showed a significant decrease in the effects indicating its chelating and neuroprotective effect. This study emphasises the transgenerational neurotoxic effect of lead, leading to early onset of major neurodegenerative disorders and its therapeutic interventions.

Alzheimer s & DementiaVol. 21(S1)
Manipal Academy of Higher Education (IN)
Openalex Percentile: Top 25%
Garlic and Onion Studies
DOIOpen Access PDFOpenAlex
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Maternal and early life exposure induced AD‐ like pathophysiology and its mitigation by allicin — Aluru Parithathvi · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS