Trajectories of genetic risk across dimensions of alcohol use behaviors

Genetic associations appear to differ not only between alcohol use behaviors, but also across developmental time points and across cohorts, highlighting the need for genetic studies to take such heterogeneity into account. Individual-level genetic profiles may be useful to point to personalized intervention timelines, particularly for individuals with high genetic risk scores for alcohol problems.

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Publication Details

Journal
Addiction
Published
2025-12-23
DOI
https://doi.org/10.1111/add.70292
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Trajectories of genetic risk across dimensions of alcohol use behaviors

Addiction
Genetic Associations and Epidemiology
article

Trajectories of genetic risk across dimensions of alcohol use behaviors

article en

Abstract

Genetic associations appear to differ not only between alcohol use behaviors, but also across developmental time points and across cohorts, highlighting the need for genetic studies to take such heterogeneity into account. Individual-level genetic profiles may be useful to point to personalized intervention timelines, particularly for individuals with high genetic risk scores for alcohol problems.

Addiction
Rutgers, The State University of New Jersey (US), University of Helsinki (FI), SUNY Downstate Health Sciences University (US), Virginia Commonwealth University (US), VA NY Harbor Healthcare System (US), Johnson University (US), Rutgers Sexual and Reproductive Health and Rights (NL), Amsterdam Neuroscience (NL), Environmental and Occupational Health Sciences Institute (US), Indiana University Bloomington (US), Institute for Molecular Medicine Finland (FI), Cognitive Research (United States) (US), Vrije Universiteit Amsterdam (NL)
Virginia Commonwealth University, Wellcome Trust, Broad Institute, Georgia Clinical and Translational Science Alliance, University of Bristol, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, National Institutes of Health, University of North Carolina at Chapel Hill, Medical Research Council, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute of Child Health and Human Development, National Center for Research Resources, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development, FP7 Health
Good health and well-being
Openalex Percentile: Top 25%
Genetic Associations and Epidemiology
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