Association Between Cortical Magnetic Susceptibility and Iron Levels in Community‐Based Older Adults: A Quantitative study of in‐vivo and post‐mortem analysis
This study established a significant positive association between cortical magnetic susceptibility and iron levels in the cortex in the same community-based older adults. The data from both in-vivo QSM and post-mortem tissue analysis suggest the potential for estimation of iron concentrations based on magnetic susceptibility values, with applications in future studies of iron dysregulation in neurodegenerative diseases.
Authors
- Mohammad Rakeen Niaz
- Shengwei Zhang (ORCID: https://orcid.org/0000-0001-9468-9635)
- Rasheed Abid
- Scott Ayton (ORCID: https://orcid.org/0000-0002-3479-2427)
- Md Tahmid Yasar
- Abdur Raquib Ridwan (ORCID: https://orcid.org/0000-0002-6600-7059)
- Konstantinos Arfanakis (ORCID: https://orcid.org/0000-0001-9705-597X)
- Arnold M Evia (ORCID: https://orcid.org/0000-0003-2262-890X)
- Yingjuan Wu (ORCID: https://orcid.org/0000-0002-0580-306X)
- Ashley Bush
- Julie A Schneider
- David A. A. Bennett
Institutions
- Rush University Medical Center (US)
- Illinois Institute of Technology (US)
- Florey Institute of Neuroscience and Mental Health (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097948
- Primary Topic
- Electromagnetic Fields and Biological Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00