A Biochemical Analysis of LINC00298 RNA's and How It May Contribute to the Development of Alzheimer's Disease

Through analysis of LINC00298 RNA's 24 protein binding partners, it was determined that LINC00298 RNA may play significant roles in neuronal development, proliferation, and cellular organization. Furthermore, analysis of LINC00298 RNA's interactome indicated that LINC00298 RNA is capable of intracellular motility with dual localization in the nucleus and the cytosol. This biochemical characterization of LINC00298 RNA has shed light on its role in Alzheimer's Disease pathogenesis.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_099861
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

A Biochemical Analysis of LINC00298 RNA's and How It May Contribute to the Development of Alzheimer's Disease

Rachel A Hellmann Whitaker
Alzheimer s & Dementia
Cancer-related molecular mechanisms research
article

A Biochemical Analysis of LINC00298 RNA's and How It May Contribute to the Development of Alzheimer's Disease

Rachel A Hellmann Whitaker
article en

Abstract

Through analysis of LINC00298 RNA's 24 protein binding partners, it was determined that LINC00298 RNA may play significant roles in neuronal development, proliferation, and cellular organization. Furthermore, analysis of LINC00298 RNA's interactome indicated that LINC00298 RNA is capable of intracellular motility with dual localization in the nucleus and the cytosol. This biochemical characterization of LINC00298 RNA has shed light on its role in Alzheimer's Disease pathogenesis.

Alzheimer s & DementiaVol. 21(S1)
University of Minnesota Medical Center (US)
Openalex Percentile: Top 34%
Cancer-related molecular mechanisms research
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