Assessing peripheral inflammation at single‐cell resolution in DS people at different stages of AD
This is the largest study to date integrating high-throughput single-cell technologies with multimodal biomarker data in DS, providing key insights into the role of the peripheral immune system across AD stages and the presence of AD pathological hallmarks, particularly in the unique DS population.
Authors
- Bessy Benejam (ORCID: https://orcid.org/0000-0002-6789-8615)
- Natalia Valle‐Tamayo
- Laura Videla (ORCID: https://orcid.org/0000-0002-9748-8465)
- María Carmona‐Iragui (ORCID: https://orcid.org/0000-0001-6914-2339)
- Oriol Dols‐Icardo (ORCID: https://orcid.org/0000-0003-2656-8748)
- Alexandre Bejanin (ORCID: https://orcid.org/0000-0002-9958-0951)
- Juan M. Fortea (ORCID: https://orcid.org/0000-0002-1340-638X)
- Esther Álvarez‐Sánchez
- Daniel Alcolea
- Joaquim Aumatell Escabias
- Mateus Rozalem Aranha
- Laia Muñoz
Institutions
- Universitat Autònoma de Barcelona (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102800
- Primary Topic
- Down syndrome and intellectual disability research
- Type
- article
- Field-Weighted Citation Impact
- 0.00