AN EXPERIMENTAL STUDY ON ANTIHYPERURICEMIC ACTIVITY IN POTASSIUM OXONATE INDUCED RAT MODEL USING HOMOEOPATHIC MEDICINE LITHIUM CARBONICUM

Hyperuricemia belongs to ICD-10 Code E79.0, is the most common disease which affects patients of all age groups and gender. Until their joints, kidneys, hearts, or other organs are impacted, the majority of people with elevated uric acid will not exhibit any symptoms. Gout-like symptoms are caused by a prolonged increase in blood uric acid. The course of disease pathology can be stopped if the elevated serum uric acid level is identified and prompt therapy is initiated. Long-term usage of the current standard treatment may have some negative effects on other important organs. For long-term care, homoeopathy will be an excellent choice because uric acid levels will fluctuate frequently. As a holistic approach, homoeopathy lowers uric acid levels and stops pathology from developing. In this study Homoeopathic medicine Lithium carbonicum 6C and 30C were used to show antihyperuricemic activity in hyperuricemia induced rat models. The rats were split up into five groups. Group 1 did not receive any medicine or induction. After an hour of fasting, other groups received an intraperitonial injection of potassium oxonate. After producing hyoeruricemia, the other three groups received an intervention, while Group 2 served as a negative control. Along with a histological study, the levels of creatinine and uric acid in the serum were measured. The result shows that when compared to allopurinol and lithium carbonicum 6C, the combined findings of the uric acid level and histopathological study demonstrated notable and consistent changes in lithium carbonicum 30C.