Elucidating the Interaction Dynamics Between a Novel Terpolymer and Aβ42: Unlocking Therapeutic Potential for Alzheimer's Disease

This study highlights the capability of the terpolymer in modulating Aβ42 aggregation dynamics, mitigating toxic oligomer formation and alleviating its neurotoxic effects. These findings present a promising approach for developing polymer-based therapies targeting Alzheimer's disease, offering a novel pathway to combat neurodegeneration. References Okumura, H., J Phys Chem B 2023, 127 (51), 10931-10940. Park E, et al. Advanced Science. 2023, 10(12):2207238. Li, L.Y.; Park, E. et al. Nanotoxicology 2024, 1-20. Li, L.Y.; Park, E. et al. Nanotoxicology 2024, 1-20.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_103257
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Elucidating the Interaction Dynamics Between a Novel Terpolymer and Aβ42: Unlocking Therapeutic Potential for Alzheimer's Disease

Lily Yi Li, Jeffrey T. Henderson, Sako Mirzaie, Xiao Yu Wu et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Elucidating the Interaction Dynamics Between a Novel Terpolymer and Aβ42: Unlocking Therapeutic Potential for Alzheimer's Disease

Lily Yi Li, Jeffrey T. Henderson, Sako Mirzaie, Xiao Yu Wu, P. E. Fraser, Chunsheng He
article en

Abstract

This study highlights the capability of the terpolymer in modulating Aβ42 aggregation dynamics, mitigating toxic oligomer formation and alleviating its neurotoxic effects. These findings present a promising approach for developing polymer-based therapies targeting Alzheimer's disease, offering a novel pathway to combat neurodegeneration. References Okumura, H., J Phys Chem B 2023, 127 (51), 10931-10940. Park E, et al. Advanced Science. 2023, 10(12):2207238. Li, L.Y.; Park, E. et al. Nanotoxicology 2024, 1-20. Li, L.Y.; Park, E. et al. Nanotoxicology 2024, 1-20.

Alzheimer s & DementiaVol. 21(S1)
University of Toronto (CA)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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