The role of microbiota‐derived exosomes in Alzheimer's disease and dementia progression and management
This study underscores the importance of microbiota-derived exosomes in understanding Alzheimer's disease and dementia progression. The findings suggest the gut-brain axis, mediated in part by these exosomes, represents a promising avenue for future research and effective therapeutic interventions as targeting these exosomes could offer novel therapeutic strategies for managing neurodegenerative diseases. However, further studies are needed to fully elucidate the mechanisms involved and translate these findings into clinical applications. This work contributes to the growing body of evidence supporting the microbiota-gut-brain axis as a critical area of investigation for neurodegenerative disease research.
Authors
- Chukwuebuka Asogwa (ORCID: https://orcid.org/0000-0003-4692-8106)
- Ajibola Moshood
- Fatola Ayomide
- Henry Demian Oyoyo
- Jonas Ibekwe
- Olatunji Zion
- Ogbeide Marvellous Aghahowa
- Olarenwaju Timileyin
Institutions
- University of Ibadan (NG)
- Forestry Research Institute of Nigeria (NG)
- University College Hospital, Ibadan (NG)
- University of Benin Teaching Hospital (NG)
- University of Benin (NG)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102839
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00