Cardiac sarcoidosis: new insights beyond the granuloma using spatial proteomics
Spatial proteomics revealed novel features of the CS microenvironment and identified a distinct immune signature in tissue lacking overt inflammation. These findings may improve diagnostic accuracy in clinical biopsies from patients with suspected CS.
Authors
- Kenneth B. Margulies (ORCID: https://orcid.org/0000-0002-8093-4465)
- Therese Bittermann (ORCID: https://orcid.org/0000-0002-8576-0193)
- Eliot Peyster (ORCID: https://orcid.org/0000-0002-3350-3136)
- Paco E. Bravo (ORCID: https://orcid.org/0000-0002-0022-4376)
- D. Robertson Smith
Institutions
- University City Science Center (US)
- Children's Hospital of Philadelphia (US)
- The University of Queensland (AU)
- Wesley Hospital (AU)
- University of Pennsylvania (US)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1093/eurheartj/ehaf990
- Citations
- 1
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16