Mechanical displacement of retinal arterial embolus during vitrectomy: A simplified surgical approach and literature review

PurposeThe management of retinal artery occlusion (RAO) remains controversial and lacks standardized guidelines. We report a case of branch retinal artery occlusion (BRAO) treated with pars plana vitrectomy (PPV) and mechanical embolus displacement 22 h after onset, along with a focused practical review of current surgical strategies.MethodsA 50-year-old man with type 2 diabetes and hypertension presented with sudden visual loss and an inferior field defect in the left eye. After unsuccessful digital massage, IOP-lowering therapy, and anterior chamber paracentesis, a 25-G three-port PPV was performed 22 h after symptom onset. Posterior vitreous detachment was induced; intraoperative IOP was set at 8 mmHg; a diamond-dusted membrane scraper was used to gently displace and fragment the embolus distally. A PubMed search for qualitative synthesis identified 20 studies (61 eyes).ResultsRetinal perfusion was restored intraoperatively. Best-corrected visual acuity improved from counting fingers to 6/9 at 1 week and 6/6 at 1 month, remaining stable at 6 months. OCT showed resolution of inner retinal edema; fluorescein angiography confirmed complete reperfusion without recurrence. Literature analysis compared surgical approaches regarding PPV technique, invasiveness, timing, and visual outcomes versus non-invasive strategies.ConclusionsPPV with minimally invasive embolus manipulation may restore retinal perfusion and achieve meaningful visual recovery beyond the conventional 4-6-h therapeutic window. This case in association with the reviewed literature suggest that in selected patients, vitrectomy, controlled IOP and targeted instrumentation is a viable and relatively safe option. Prospective trials are needed to define optimal timing, techniques, and patient selection.

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Journal
European Journal of Ophthalmology
Published
2025-12-24
DOI
https://doi.org/10.1177/11206721251392042
Primary Topic
Retinal and Optic Conditions
Type
article
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article

Mechanical displacement of retinal arterial embolus during vitrectomy: A simplified surgical approach and literature review

Guido Prigione, Marco Anastasi, Gregorio Lo Giudice, Erika Bonacci et al.
European Journal of Ophthalmology
Retinal and Optic Conditions
article

Mechanical displacement of retinal arterial embolus during vitrectomy: A simplified surgical approach and literature review

Guido Prigione, Marco Anastasi, Gregorio Lo Giudice, Erika Bonacci, R Asaria, Elena Veronica Perozzo, Ayushi Gupta, Ajay Mohite, Emilio Pedrotti
article en

Abstract

PurposeThe management of retinal artery occlusion (RAO) remains controversial and lacks standardized guidelines. We report a case of branch retinal artery occlusion (BRAO) treated with pars plana vitrectomy (PPV) and mechanical embolus displacement 22 h after onset, along with a focused practical review of current surgical strategies.MethodsA 50-year-old man with type 2 diabetes and hypertension presented with sudden visual loss and an inferior field defect in the left eye. After unsuccessful digital massage, IOP-lowering therapy, and anterior chamber paracentesis, a 25-G three-port PPV was performed 22 h after symptom onset. Posterior vitreous detachment was induced; intraoperative IOP was set at 8 mmHg; a diamond-dusted membrane scraper was used to gently displace and fragment the embolus distally. A PubMed search for qualitative synthesis identified 20 studies (61 eyes).ResultsRetinal perfusion was restored intraoperatively. Best-corrected visual acuity improved from counting fingers to 6/9 at 1 week and 6/6 at 1 month, remaining stable at 6 months. OCT showed resolution of inner retinal edema; fluorescein angiography confirmed complete reperfusion without recurrence. Literature analysis compared surgical approaches regarding PPV technique, invasiveness, timing, and visual outcomes versus non-invasive strategies.ConclusionsPPV with minimally invasive embolus manipulation may restore retinal perfusion and achieve meaningful visual recovery beyond the conventional 4-6-h therapeutic window. This case in association with the reviewed literature suggest that in selected patients, vitrectomy, controlled IOP and targeted instrumentation is a viable and relatively safe option. Prospective trials are needed to define optimal timing, techniques, and patient selection.

European Journal of Ophthalmology
University of Verona (IT), The Royal Free Hospital (GB), Ospedale Sacro Cuore Don Calabria (IT), University College London (GB)
Good health and well-being
Openalex Percentile: Top 30%
Retinal and Optic Conditions
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