Endophenotypes of Late‐Onset Alzheimer's Disease in Mouse Models Expressing IL1RAP Risk Alleles
Here we present two novel mouse strains of LOAD, expressing human-relevant genetic backgrounds aimed at investigating IL1RAP function as a model of human disease and potential target for therapeutic intervention against neurodegeneration.
Authors
- Kevin P. Kotredes (ORCID: https://orcid.org/0000-0001-7874-4139)
- Gareth R. Howell (ORCID: https://orcid.org/0000-0003-0565-6474)
- Michael Sasner (ORCID: https://orcid.org/0000-0002-6612-6111)
- Ravi S. Pandey (ORCID: https://orcid.org/0000-0001-9567-2851)
- Paul R. Territo (ORCID: https://orcid.org/0000-0003-0460-332X)
- Adrian L Oblak
- Stacey J Sukoff Rizzo
- Bruce T. Lamb
- MODEL‐AD
- Gregory W Carter
Institutions
- University of Pittsburgh (US)
- Jackson Laboratory (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_102802
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00