TOX‐AD: Imaging of Environmental Neurotoxicants Accumulated in Mouse Brains
MODEL-AD mice exposed to Pb, Cd, or As accumulate neurotoxicants in blood and brain that can be detected, imaged, and quantified by ICP-MS solution analysis and LA-ICP-MS imaging. References: [1] R.A. Armstrong, Risk factors for Alzheimer's disease. Folia Neuropathologica., 2019, 57, 87-105. [2] World Health Organization. 10 chemicals of public health concern. 2020.
Authors
- Kevin P. Kotredes (ORCID: https://orcid.org/0000-0001-7874-4139)
- Nicola Lupoli
- Olga Minaeva (ORCID: https://orcid.org/0000-0002-7911-6510)
- Gareth R. Howell (ORCID: https://orcid.org/0000-0003-0565-6474)
- Juliet A. Moncaster (ORCID: https://orcid.org/0000-0002-7849-4325)
- Paul R. Territo (ORCID: https://orcid.org/0000-0003-0460-332X)
- Ning Hua
- Zeynep Sarica
- Lee E Goldstein
Institutions
- Boston University (US)
- Jackson Laboratory (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_101024
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00