A unique pattern of T2 FLAIR white matter hyperintensities and related co‐localizing neuropathology associated with repetitive head impacts
We provide empirical support for exposure to RHI as potentially leading to a unique pattern of WMH. Importantly, histopathological evidence showed that the RHI-WMH co-localized with RHI and CTE-related neuropathologies at the depths of the sulci.
Authors
- Adam M. Brickman (ORCID: https://orcid.org/0000-0002-5125-8226)
- Laura J. Balcer (ORCID: https://orcid.org/0000-0002-5136-4539)
- Annalise E. Miner (ORCID: https://orcid.org/0000-0002-9336-2419)
- Robert C. Cantu (ORCID: https://orcid.org/0009-0002-4300-4063)
- Charles Bernick (ORCID: https://orcid.org/0000-0003-4040-3587)
- Michael L. Alosco (ORCID: https://orcid.org/0000-0002-8113-8428)
- Mohamad J. Alshikho
- Chad W. Farris (ORCID: https://orcid.org/0000-0002-1133-3834)
- Yorghos Tripodis
- Charles Adler
- Ann C. McKee
- Jenna R. Groh
- Martha E. Shenton
- Thor D. Stein
- Robert A. Stern
- Anna Cui
- Sylvain Bouix
- David W. Dodick
- Jeffrey L. Cummings
- Eric M. Reiman
- Jesse Mez
- Michael J. Coleman
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- Boston Medical Center (US)
- Cleveland Clinic (US)
- University of Nevada, Las Vegas (US)
- Université du Québec à Montréal (CA)
- Lou Ruvo Brain Institute (US)
- Mayo Clinic in Arizona (US)
- Banner Sun Health Research Institute (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_096739
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00