Ferroptosis and Neurodegeneration: Unlocking New Therapeutic Pathways in Alzheimer's Disease

According to recent data, ferroptosis linked to neurodegeneration is significantly influenced by iron-loaded microglia. In order to provide useful knowledge for the future treatment and prevention of AD, we examine here the primary pathways regulating ferroptosis in AD as well as the possible connection between AD and ferroptosis. Keyword: Alzheimer, β-amyloid plaque, ferroptosis, antioxidant, glutathione, neurodegeneration.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_105436
Citations
1
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
1.52
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article

Ferroptosis and Neurodegeneration: Unlocking New Therapeutic Pathways in Alzheimer's Disease

Ritika Saini
1 citations
Alzheimer s & Dementia
Ferroptosis and cancer prognosis
1.52
article

Ferroptosis and Neurodegeneration: Unlocking New Therapeutic Pathways in Alzheimer's Disease

Ritika Saini
article en
1 citations

Abstract

According to recent data, ferroptosis linked to neurodegeneration is significantly influenced by iron-loaded microglia. In order to provide useful knowledge for the future treatment and prevention of AD, we examine here the primary pathways regulating ferroptosis in AD as well as the possible connection between AD and ferroptosis. Keyword: Alzheimer, β-amyloid plaque, ferroptosis, antioxidant, glutathione, neurodegeneration.

Alzheimer s & DementiaVol. 21(S1)
J.C. Bose University of Science & Technology, YMCA (IN)
Openalex Percentile: Top 12%
Ferroptosis and cancer prognosis
1.52
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Ferroptosis and Neurodegeneration: Unlocking New Therapeutic Pathways in Alzheimer's Disease — Ritika Saini · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS