Genetic Variants and Brain Tau Levels
We identified genetic variants potentially associated with MTL tau accumulation in NHB participants, located in genes having prior associations with AD risk factors. We will assess these relationships in larger samples when they become available in HABS-HD. If confirmed, these results will enhance our understanding of dementia risk across ethnoracial groups and guide future research into personalized medicine and precision healthcare.
Authors
- Meredith N. Braskie (ORCID: https://orcid.org/0000-0002-6439-4243)
- Koral V Wheeler
- Danielle Luu
- Maxwell W Hand (ORCID: https://orcid.org/0009-0003-1732-3324)
- Sid E. O'Bryant
- Robert Barber
- Kristine Yaffe
- Noelle Lee
- Nicole Phillips
- Arthur W. Toga
Institutions
- University of Southern California (US)
- University of North Texas (US)
- University of North Texas Health Science Center (US)
- University of California, San Francisco (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105772
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00