Biofluid‐based biomarker discovery using brain biopsy data as the reference standard

Our study confirms and suggests novel biomarker candidates associated with ATN pathology and shows the temporal profile of different groups of CSF proteins across the AD continuum in three independent cohorts. The novel protein biomarkers could be useful for AD staging beyond the ATN framework.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_097564
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
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article

Biofluid‐based biomarker discovery using brain biopsy data as the reference standard

Henrik Zetterberg
Alzheimer s & Dementia
Cerebrospinal fluid and hydrocephalus
article

Biofluid‐based biomarker discovery using brain biopsy data as the reference standard

Henrik Zetterberg
article en

Abstract

Our study confirms and suggests novel biomarker candidates associated with ATN pathology and shows the temporal profile of different groups of CSF proteins across the AD continuum in three independent cohorts. The novel protein biomarkers could be useful for AD staging beyond the ATN framework.

Alzheimer s & DementiaVol. 21(S2)
Profu (Sweden) (SE), University of Gothenburg (SE)
Openalex Percentile: Top 38%
Cerebrospinal fluid and hydrocephalus
DOIOpen Access PDFOpenAlex
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Biofluid‐based biomarker discovery using brain biopsy data as the reference standard — Henrik Zetterberg · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS