Bifidobacterium bifidum CIP-01 attenuates metabolic dysfunction-associated steatotic liver disease induced by high-alcohol-producing Klebsiella pneumoniae
Our findings highlight B. bifidum CIP-01 as a novel therapeutic candidate for HiAlc Kpn-induced MASLD, operating through a triad of pathogen suppression, gut-liver axis repair, and metabolic regulation.
Authors
- Zihui Yu (ORCID: https://orcid.org/0000-0002-3468-7782)
- Zheng Fan (ORCID: https://orcid.org/0000-0003-1934-2521)
- X.Y. Liu
- Yuehua Ke
- Junxia Feng (ORCID: https://orcid.org/0009-0006-1610-2476)
- Guanhua Xue
- Jing Yuan (ORCID: https://orcid.org/0009-0000-8704-6762)
- Yanling Feng
- Hanqing Zhao (ORCID: https://orcid.org/0009-0009-3300-0959)
- Chao Yan (ORCID: https://orcid.org/0000-0001-5624-8636)
- Xue Ren
- Tongtong Fu (ORCID: https://orcid.org/0009-0000-6259-0235)
- Lin Gan (ORCID: https://orcid.org/0000-0001-5374-6277)
- Xinyu Jia
- Ziying Xu
- Yujie Chen
- Yang Yang
- Jinghua Cui
- Rentao Yu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Capital Institute of Pediatrics (CN)
- China National Building Materials Group (China) (CN)
Publication Details
- Journal
- Journal of Gastroenterology
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1007/s00535-025-02332-x
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00