Modulatory roles of the vagus nerve and nicotine in bleomycin-induced pulmonary fibrosis in rats
These findings highlight the anti-inflammatory role of the vagus nerve and suggest that nicotine-particularly in combination with vagotomy-may confer protective effects against early-stage pulmonary fibrosis by mitigating inflammation, oxidative stress, and pulmonary dysfunction.
Authors
- Farzaneh Ketabchi (ORCID: https://orcid.org/0000-0002-1157-3299)
- Amirreza Dehghanian (ORCID: https://orcid.org/0000-0003-0360-7468)
- Parisa Askarizadeh
Institutions
- Shiraz University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s12890-025-04071-4
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00