Gut Microbiota and Cerebrovascular Patterns in Amnestic Mild Cognitive Impairment
Consistent with previous research, we found that persons with aMCI have an altered gut microbiome relative to controls. Further, we demonstrate through metagenomics sequencing that both bacterial and viral taxa are associated with cognitive and neurovascular functioning in aMCI. Knowledge about the relationships between the microbiota, cognition, and cerebrovascular function paves the way for future studies cross-sectional and longitudinal studies.
Authors
- Alexander D. Cohen (ORCID: https://orcid.org/0000-0002-8312-4046)
- Scott S. Terhune (ORCID: https://orcid.org/0000-0003-3689-7094)
- Yang Wang (ORCID: https://orcid.org/0000-0001-9730-5975)
- John R. Kirby (ORCID: https://orcid.org/0000-0002-2612-0479)
- Laura Glass Umfleet (ORCID: https://orcid.org/0000-0001-7943-0406)
- Shawn Obarski
- Lilly Mason
- Malgorzata Franczak
- Fatima A. Aboulalazm (ORCID: https://orcid.org/0009-0004-4623-3958)
- Alexis B. Kazen (ORCID: https://orcid.org/0000-0002-5409-3877)
- Tammy Kindel
Institutions
- Medical College of Wisconsin (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_097652
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00