Elevated D-Dimer and Hypoalbuminemia as Predictors of Early Mortality in Cancer-Associated Pulmonary Embolism

D-dimer independently predicted short-term mortality in hospitalized patients with cancer with acute PE even after adjustment for metastatic status; albumin demonstrated only a borderline association. These routinely available biomarkers may support early risk assessment but should be interpreted cautiously in the context of other clinical factors. Prospective studies are needed to validate these findings.