Simple MRI Lesion Levels Improve Two-Year Prognostic Accuracy Beyond Clinical History in CADASIL
CADASIL MRI Inventory Tool lesion levels are differentially associated with CADASIL manifestations and provide independent 2-year prognostic information beyond clinical covariates. These simple measures may supplement clinical evaluation to improve short-term risk stratification and support patient selection in clinical trials.
Authors
- Dominique Hervé (ORCID: https://orcid.org/0000-0001-6197-6275)
- Stéphanie Guey (ORCID: https://orcid.org/0000-0001-6096-3595)
- M Dichgans
- Jessica Lebenberg (ORCID: https://orcid.org/0000-0002-5403-8288)
- Hugues Chabriat (ORCID: https://orcid.org/0000-0001-8436-6074)
- Yu-Wen Cheng
- Chih-Hao Chen
- Louis Lambert
- Sung-Chun Tang
- Ruiting Zhang
- Sophie Tezenas Du Montcel
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- German Center for Neurodegenerative Diseases (DE)
- Sorbonne Université (FR)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Munich Cluster for Systems Neurology (DE)
- Hôpital Lariboisière (FR)
- National Taiwan University Hospital (TW)
- Second Affiliated Hospital of Zhejiang University (CN)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Stroke
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1161/strokeaha.125.053727
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00